Anti-ALDH18A1 Polyclonal Antibody, 50.0ul

£145.11
Delivery: 2 weeks
SKU
K113608P-50.0ul
This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoproli

This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

  • Size: 50.0ul
  • Molecular Weight: 87kDa
  • Physical State: Liquid
  • Storage: Store at -20℃. Avoid freeze / thaw cycles.
  • Application: WB;IHC
  • Brand: Saint Michael
  • Catalogue No.: K113608P-50.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.

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