Anti-APOBEC3A Polyclonal Antibody, 50.0ul

£145.11
Delivery: 2 weeks
SKU
K114975P-50.0ul
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA s

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.

  • Size: 50.0ul
  • Molecular Weight: 22/23kDa
  • Physical State: Liquid
  • Storage: Store at -20℃. Avoid freeze / thaw cycles.
  • Application: WB;IHC
  • Brand: Saint Michael
  • Catalogue No.: K114975P-50.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.

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