Anti-Artemis (phospho Ser516) Polyclonal Antibody, 50.0ul
£235.81
Delivery: 2 weeks
SKU
K009394P-50.0ul
This protein exhibits single-strand specific 5'-3' exonuclease activity in isolation and acquires endonucleolytic activity on 5' and 3' hairpins and overhangs when in a complex with PRKDC. The latter activity is required specifically for the resolution of closed hairpins prior to the formation of the coding joint. May also be required for the repair of complex DSBs induced by ionizing radiation, which require substantial end-processing prior to religation by non homologous end joining.
This protein exhibits single-strand specific 5'-3' exonuclease activity in isolation and acquires endonucleolytic activity on 5' and 3' hairpins and overhangs when in a complex with PRKDC. The latter activity is required specifically for the resolution of closed hairpins prior to the formation of the coding joint. May also be required for the repair of complex DSBs induced by ionizing radiation, which require substantial end-processing prior to religation by non homologous end joining.
- Size: 50.0ul
- Molecular Weight: 78kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze / thaw cycles.
- Application: ELISA;IHC;WB
- Brand: Saint Michael
- Catalogue No.: K009394P-50.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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