Anti-BCCIP Polyclonal Antibody, 100.0ul

£507.89
Delivery: 2 weeks
SKU
K005929P-100.0ul
This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated

This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.

  • Size: 100.0ul
  • Molecular Weight: 36kDa
  • Physical State: Liquid
  • Storage: Store at -20℃. Avoid freeze/thaw cycles.
  • Application: IHC;WB
  • Brand: Saint Michael
  • Catalogue No.: K005929P-100.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.

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