Anti-Brd4 Polyclonal Antibody, 100.0ul
BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms, longer variant has a C-terminus region with a praline and glutamine-rich domains. BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus.
- Size: 100.0ul
- Molecular Weight: 156kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze / thaw cycles.
- Application: WB
- Brand: Saint Michael
- Catalogue No.: K010192P-100.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.