Anti-CARD8 Polyclonal Antibody, 50.0ul

The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins; which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome; a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation; CASP1-dependent IL1B secretion; and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.

• Size: 50.0ul
• Molecular Weight: 32/44/48/49/55/61kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Application: IHC
• Brand: Saint Michael
• Catalogue No.: K115032P-50.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.