Anti-CASP10 Polyclonal Antibody, 100.0ul
£243.06
Delivery: 2 weeks
SKU
K110451P-100.0ul
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.1 Publication Isoform 7 can enhance NF-kappaB activity but promotes only slight apoptosis.Isoform C is proteolytically inactive.
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.1 Publication Isoform 7 can enhance NF-kappaB activity but promotes only slight apoptosis.Isoform C is proteolytically inactive.
- Size: 100.0ul
- Molecular Weight: 28/31/52/55/59kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze/thaw cycles.
- Application: IHC
- Brand: Saint Michael
- Catalogue No.: K110451P-100.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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