Anti-CASP4/CASP5 Polyclonal Antibody, 20.0ul

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

• Size: 20.0ul
• Molecular Weight: 13/18/30/33/37/42/43/50/51kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Application: IHC
• Brand: Saint Michael
• Catalogue No.: K113925P-20.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.