Anti-CASP4 Polyclonal Antibody, 50.0ul

This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is 'caspase 4, apoptosis-related cysteine peptidase', this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.

• Size: 50.0ul
• Molecular Weight: 43/37/13/30/18kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Application: WB
• Brand: Saint Michael
• Catalogue No.: K004571P-50.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.