Anti-CASP8 Polyclonal Antibody, 100.0ul
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD.
- Size: 100.0ul
- Molecular Weight: 55/53/45/57/27/25/32/30/61kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze/thaw cycles.
- Application: IF;IHC;WB
- Brand: Saint Michael
- Catalogue No.: K001600P-100.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.