Anti-Caspase-1 Monoclonal Antibody, 50.0ul

£408.13
Delivery: 2 weeks
SKU
K011502M-50.0ul
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family.Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits large and small that dimerize to form the active enzyme.This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family.Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits large and small that dimerize to form the active enzyme.This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1 a cytokine involved in the processes such as inflammation septic shock and wound healing.This gene has been shown to induce cell apoptosis and may function in various developmental stages.Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease.Alternative splicing of this gene results in five transcript variants encoding distinct isoforms.[provided by RefSeq].

  • Size: 50.0ul
  • Molecular Weight: 10KDa/29KDa/35KDa/42KDa/45KDa
  • Physical State: Liquid
  • Storage: Store at -20℃.Avoid freeze/thaw cycles.
  • Application: WB;ELISA
  • Brand: Saint Michael
  • Catalogue No.: K011502M-50.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.

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