Anti-Caspase 1/p20/p10 Polyclonal Antibody, 50.0ul

CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products (PMID:21804020). It has 5 isoforms produced by alternative splicing. It can recognize all the five isoforms of caspase 1. It also can recognize p45 procaspase and the mature fragments p10 and p20.

• Size: 50.0ul
• Molecular Weight: 45kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Application: WB;IHC;ELISA;IF
• Brand: Saint Michael
• Catalogue No.: K010101P-50.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.