Anti-CD154 Monoclonal Antibody, 1.0mg

CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.

• Size: 1.0mg
• Physical State: Liquid
• Storage: Store at 4℃ in dark.Do not freeze.
• Application: FCM
• Brand: Saint Michael
• Catalogue No.: K011326M-1.0mg

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.