Anti-CD163(APC) Monoclonal antibody, 25.0T
CD163, also known as M130, is a membrane glycoprotein which belongs to the scavenger receptor superfamily (PMID: 8370408). It is an acute phase-regulated and signal-inducing macrophage protein expressed exclusively in monocytes and tissue macrophages (PMID: 11196644). CD163 mediates endocytosis of haptoglobin-haemoglobin complexes (PMID: 11196644). The uptake of haptoglobin by macrophages contributes to the recycling of iron and also to the inflammatory response (PMID: 22900885). Soluble CD163 (sCD163), as a result of ectodomain shedding during inflammatory activation of macrophages, circulates in blood and has been suggested as a plasma/serum marker for macrophage activity (PMID: 12570164).
- Size: 25.0T
- Molecular Weight: 125kDa
- Physical State: Liquid
- Storage: Store at 2-8℃. Avoid light.
- Application: FCM
- Brand: Saint Michael
- Catalogue No.: K010038M-25.0T
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.