Anti-CD279/PD-1(APC) Monoclonal Antibody, 100.0T
Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
- Size: 100.0T
- Molecular Weight: 32kDa
- Physical State: Liquid
- Storage: Store at 2-8℃. Avoid exposure to light.
- Application: FCM
- Brand: Saint Michael
- Catalogue No.: K010115M-100.0T
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.