Anti-CD45(PE/Cyanine7) Monoclonal Antibody, 100.0T

CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

• Size: 100.0T
• Molecular Weight: 180-240kDa
• Physical State: Liquid
• Storage: Store at 2-8℃. Avoid light.
• Application: FCM
• Brand: Saint Michael
• Catalogue No.: K010111M-100.0T

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.