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Anti-CD8a(AF488) Monoclonal Antibody, 100.0ug

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£190.46
Delivery: 2 weeks
SKU
K011462M-100.0ug
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CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains.It can be present as a homodimer of CD8 or as a heterodimer of CD8 and CD8 (PMID: 3264320;8253791).CD8 is found on most thymocytes.The majority of class I-restricted T cells express mostly the CD8 heterodimer while CD8 homodimers alone have been found on some gut intraepithelial T cells on some T cell receptor (TCR) T cells and on NK cells (PMID: 2111591;1831127;8420975).CD8 acts as a co-receptor that binds to MHC class-

CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains.It can be present as a homodimer of CD8 or as a heterodimer of CD8 and CD8 (PMID: 3264320;8253791).CD8 is found on most thymocytes.The majority of class I-restricted T cells express mostly the CD8 heterodimer while CD8 homodimers alone have been found on some gut intraepithelial T cells on some T cell receptor (TCR) T cells and on NK cells (PMID: 2111591;1831127;8420975).CD8 acts as a co-receptor that binds to MHC class-I and participates in cytotoxic T cell activation (PMID: 8499079).During T cell development CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084).

  • Size: 100.0ug
  • Molecular Weight: 27kDa
  • Physical State: Liquid
  • Storage: Store at 2-8℃ in dark.Do not freeze.
  • Application: IF
  • Brand: Saint Michael
  • Catalogue No.: K011462M-100.0ug

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.

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