Anti-CMTM8 Polyclonal Antibody, 100.0ul
£243.06
Delivery: 2 weeks
SKU
K113113P-100.0ul
CMTM8, also known as CKLFSF8, is a member of the chemokine-like factor superfamily (CKLFSF).Proteins of this family share similarity with both the chemokine and the transmembrane 4 superfamilies. CMTM8 is an attenuator of EGF-induced signaling (PMID: 16263120).Overexpression of CMTM8 accelerates ligand-induced clearance of EGFR from the cell surface and induces apoptosis via caspase-dependent and -independent pathways (PMID: 17149703).An alternative splice form of CMTM8, CMTM8-v2, arises from a
CMTM8, also known as CKLFSF8, is a member of the chemokine-like factor superfamily (CKLFSF).Proteins of this family share similarity with both the chemokine and the transmembrane 4 superfamilies. CMTM8 is an attenuator of EGF-induced signaling (PMID: 16263120).Overexpression of CMTM8 accelerates ligand-induced clearance of EGFR from the cell surface and induces apoptosis via caspase-dependent and -independent pathways (PMID: 17149703).An alternative splice form of CMTM8, CMTM8-v2, arises from a deletion of exon 2. CMTM8-v2 maintains the ability to induce apoptosis (PMID: 17681841).
- Size: 100.0ul
- Molecular Weight: 13/20kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze / thaw cycles.
- Application: IHC
- Brand: Saint Michael
- Catalogue No.: K113113P-100.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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