Anti-DDX42 Polyclonal Antibody, 50.0ul
ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.
- Size: 50.0ul
- Molecular Weight: 90/103kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze / thaw cycles.
- Application: WB
- Brand: Saint Michael
- Catalogue No.: K115807P-50.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.