Anti-DNMT3B Polyclonal Antibody, 100.0ul

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

• Size: 100.0ul
• Molecular Weight: 77-95kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze/thaw cycles.
• Application: WB;IF
• Brand: Saint Michael
• Catalogue No.: K003525P-100.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.