Anti-E2F6 Polyclonal Antibody, 20.0ul

£72.56
Delivery: 2 weeks
SKU
K110519P-20.0ul
Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling com

Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.

  • Size: 20.0ul
  • Molecular Weight: 23/28/32kDa
  • Physical State: Liquid
  • Storage: Store at -20℃. Avoid freeze/thaw cycles.
  • Application: WB
  • Brand: Saint Michael
  • Catalogue No.: K110519P-20.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.

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