Anti-ELOVL1 Polyclonal Antibody, 50.0ul

Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle (PubMed:29496980, PubMed:30487246).This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and monounsaturated acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis (PubMed:20937905).Indirectly inhibits RPE65 via production of VLCFAs.

• Size: 50.0ul
• Molecular Weight: 29/33kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Application: WB;IHC
• Brand: Saint Michael
• Catalogue No.: K114990P-50.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.