Anti-EMR1 Polyclonal Antibody, 100.0ul

EMR1 (EGF-like module containing mucin-like hormone receptor 1), also known as Adhesion G protein-coupled receptor E1 (ADGRE1), is a surface receptor with seven transmembrane segments that belongs to the EGF-7-transmembrane family of G protein-coupled receptors (PMID: 14647991, 7601460). EMR1 expression is restricted to eosinophilic granulocytes, where expression is overlapping with the eotaxin receptor CCR3 and the immunoglobulin-like lectin Siglec-8. Absence on other leukocytes, including basophils, implies that EMR1 is a highly specific marker for eosinophils in humans and may be used as a novel therapeutic target for eosinophilic disorders(PMID: 17823986, 24530099). F4/80, the murine homolog of EMR1, is a marker of murine macrophage. The apparent molecular weigh of F4/80 is 160 kDa, which is lager than the calculated molecular weight due to post-translational modifications (PMID: 7308288; 8647179).

• Size: 100.0ul
• Molecular Weight: 90kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Application: ELISA;WB;IHC;IF
• Brand: Saint Michael
• Catalogue No.: K009778P-100.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.