Anti-FLNA Polyclonal Antibody, 50.0ul

Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNB may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking ;Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance ;During the axon guidance process, required for growth cone collapse induced by SEMA3A-mediated stimulation of neurons

• Size: 50.0ul
• Molecular Weight: 280/281kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Application: WB
• Brand: Saint Michael
• Catalogue No.: K112940P-50.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.