Anti-GSK3B Monoclonal Antibody, 100.0ul

In Wnt signaling, GSK3B forms a multimeric complex with APC, AXIN1 and CTNNB1/beta-catenin and phosphorylates the N-terminus of CTNNB1 leading to its degradation mediated by ubiquitin/proteasomes. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA.

• Size: 100.0ul
• Molecular Weight: 47kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze/thaw cycles.
• Application: IHC;WB
• Brand: Saint Michael
• Catalogue No.: K000187M-100.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.