Anti-HORMAD2 Polyclonal Antibody, 20.0ul

£72.56
Delivery: 2 weeks
SKU
K109554P-20.0ul
Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation o

Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity).

  • Size: 20.0ul
  • Molecular Weight: 35kDa
  • Physical State: Liquid
  • Storage: Store at -20℃. Avoid freeze/thaw cycles.
  • Application: WB;IHC
  • Brand: Saint Michael
  • Catalogue No.: K109554P-20.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.

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