Anti-IKZF1 Polyclonal Antibody, 100.0ul

Transcription regulator of hematopoietic cell differentiation (PubMed:17934067).Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity).

• Size: 100.0ul
• Molecular Weight: 58kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze/thaw cycles.
• Application: IF;WB;ChIP
• Brand: Saint Michael
• Catalogue No.: K003035P-100.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.