Anti-IL-12p70 Monoclonal Antibody, 1.0mg
£491.57
Delivery: 2 weeks
SKU
K011343M-1.0mg
IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice
IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
- Size: 1.0mg
- Physical State: Liquid
- Storage: Store at 4℃ in dark.Do not freeze.
- Application: FCM
- Brand: Saint Michael
- Catalogue No.: K011343M-1.0mg
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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