Anti-IL-1B Monoclonal Antibody, 100.0ul
Potent pro-inflammatory cytokine Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6 Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
- Size: 100.0ul
- Molecular Weight: 31 kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze/thaw cycles.
- Application: WB
- Brand: Saint Michael
- Catalogue No.: K011362M-100.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.