Anti-IL16 Polyclonal Antibody, 50.0ul
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
- Size: 50.0ul
- Molecular Weight: 59/67/142kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze / thaw cycles.
- Application: WB
- Brand: Saint Michael
- Catalogue No.: K112415P-50.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.