Anti-ITGB4 Polyclonal Antibody, 100.0ul

Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464).

• Size: 100.0ul
• Molecular Weight: 107/194/195/201/202kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze/thaw cycles.
• Application: WB
• Brand: Saint Michael
• Catalogue No.: K110413P-100.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.