Anti-KLHDC4 Polyclonal Antibody, 100.0ul
KLHDC4 is a 520 amino acid protein that contains six kelch repeats and exists as three alternatively spliced isoforms. The gene encoding KLHDC4 maps to human chromosome 16q24.2 and mouse chromosome 8 E1. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.
- Size: 100.0ul
- Molecular Weight: 51/54/58kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze/thaw cycles.
- Application: IHC
- Brand: Saint Michael
- Catalogue No.: K111191P-100.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.