Anti-MBNL1 Polyclonal Antibody, 50.0ul

This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.

• Size: 50.0ul
• Molecular Weight: 42kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze/thaw cycles.
• Application: IF;WB;IHC
• Brand: Saint Michael
• Catalogue No.: K000457P-50.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.