Anti-MUC1 Polyclonal Antibody, 20.0ul
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways.In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
- Size: 20.0ul
- Molecular Weight: 10/17/18/22/24/25/28/30/104/121/122/123kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze/thaw cycles.
- Application: IHC
- Brand: Saint Michael
- Catalogue No.: K110468P-20.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.