Anti-NPAS4 Polyclonal Antibody, 50.0ul
Transcription factor expressed in neurons of the brain that regulates the excitatory-inhibitory balance within neural circuits and is required for contextual memory in the hyppocampus (By similarity). Plays a key role in the structural and functional plasticity of neurons (By similarity). Acts as an early-response transcription factor in both excitatory and inhibitory neurons, where it induces distinct but overlapping sets of late-response genes in these two types of neurons, allowing the synapses that form on inhibitory and excitatory neurons to be modified by neuronal activity in a manner specific to their function within a circuit, thereby facilitating appropriate circuit responses to sensory experience (By similarity). In excitatory neurons, activates transcription of BDNF, which in turn controls the number of GABA-releasing synapses that form on excitatory neurons, thereby promoting an increased number of inhibitory synapses on excitatory neurons (By similarity).
- Size: 50.0ul
- Molecular Weight: 25/87kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze/thaw cycles.
- Application: IHC
- Brand: Saint Michael
- Catalogue No.: K111103P-50.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.