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Anti-PARD3 Polyclonal Antibody, 20.0ul

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£72.56
Delivery: 2 weeks
SKU
K112166P-20.0ul
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Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688, PubMed:10954424). Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688). Targets the phosphatase PTEN to cell junctions (By similarity). Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (By similarity). The PARD6-PARD3

Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688, PubMed:10954424). Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688). Targets the phosphatase PTEN to cell junctions (By similarity). Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (By similarity). The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10934474). Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (PubMed:19812038, PubMed:27925688).

  • Size: 20.0ul
  • Molecular Weight: 109/110/113/138/141/142/146/147/150/151kDa
  • Physical State: Liquid
  • Storage: Store at -20℃. Avoid freeze / thaw cycles.
  • Application: WB;IHC
  • Brand: Saint Michael
  • Catalogue No.: K112166P-20.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.

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