Anti-phospho-AKT (Ser473) Polyclonal Antibody, 50.0ul

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT proteins all have an N-terminal pleckstrin homology domain, a serine/threonine-specific kinase domain and a C-terminal regulatory domain. These proteins are phosphorylated by phosphoinositide 3-kinase (PI3K). AKT/PI3K forms a key component of many signalling pathways that involve the binding of membrane-bound ligands such as receptor tyrosine kinases, G-protein coupled receptors, and integrin-linked kinase. These AKT proteins therefore regulate a wide variety of cellular functions including cell proliferation, survival, metabolism, and angiogenesis in both normal and malignant cells.

• Size: 50.0ul
• Molecular Weight: 56kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Application: WB;IHC;IF;FCM;ELISA
• Brand: Saint Michael
• Catalogue No.: K009354P-50.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.