Anti-Phospho-JNK1-T183/Y185+JNK2-T183/Y185+JNK3-T221/Y223 Monoclonal Antibody, 100.0ul

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]

• Size: 100.0ul
• Molecular Weight: 27/35/44/48kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Application: IF;IHC;WB
• Brand: Saint Michael
• Catalogue No.: K010067M-100.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.