Anti-PINK1 Monoclonal Antibody, 50.0ul
£453.48
Delivery: 2 weeks
SKU
K009342M-50.0ul
Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PRKN . Targets PRKN to dysfunctional depolarized mitochondria through the phosphorylation of MFN2 . Activates PRKN in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PRKN and (2) mediating phosphorylation of ubiquitin, converting PRKN to its fully-act
Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PRKN . Targets PRKN to dysfunctional depolarized mitochondria through the phosphorylation of MFN2 . Activates PRKN in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PRKN and (2) mediating phosphorylation of ubiquitin, converting PRKN to its fully-active form . Required for ubiquinone reduction by mitochondrial complex I by mediating phosphorylation of complex I subunit NDUFA10 (By similarity).
- Size: 50.0ul
- Molecular Weight: 63kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze / thaw cycles.
- Application: IF;ICC;IHC;WB
- Brand: Saint Michael
- Catalogue No.: K009342M-50.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
Write Your Own Review