Anti-PRNP Polyclonal Antibody, 50.0ul

The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 2; approximately 2 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease; fatal familial insomnia; Gerstmann-Straussler disease; Huntington disease-like 1; and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller; structurally unrelated protein; AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Nov 214]

• Size: 50.0ul
• Molecular Weight: 28kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Application: WB
• Brand: Saint Michael
• Catalogue No.: K115035P-50.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.