Anti-RNF111 Polyclonal Antibody, 100.0ul

£243.06
Delivery: 2 weeks
SKU
K113401P-100.0ul
The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative spli

The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

  • Size: 100.0ul
  • Molecular Weight: 108/109/110kDa
  • Physical State: Liquid
  • Storage: Store at -20℃. Avoid freeze / thaw cycles.
  • Application: IHC;WB
  • Brand: Saint Michael
  • Catalogue No.: K113401P-100.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.

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