Anti-SBF2 Polyclonal Antibody, 20.0ul
Guanine nucleotide exchange factor (GEF) which activates RAB21 and possibly RAB28 (PubMed:20937701, PubMed:25648148).Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (PubMed:20937701, PubMed:25648148).In response to starvation-induced autophagy, activates RAB21 which in turn binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion (PubMed:25648148).Acts as an adapter for the phosphatase MTMR2 (By similarity).Increases MTMR2 catalytic activity towards phosphatidylinositol 3, 5-bisphosphate and to a lesser extent towards phosphatidylinositol 3-phosphate (By similarity).
- Size: 20.0ul
- Molecular Weight: 129/208kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze/thaw cycles.
- Application: IHC
- Brand: Saint Michael
- Catalogue No.: K114472P-20.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.