Anti-SH3RF2 Polyclonal Antibody, 100.0ul
£243.06
Delivery: 2 weeks
SKU
K114467P-100.0ul
Has E3 ubiquitin-protein ligase activity (PubMed:24130170).Acts as an anti-apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a scaffold protein that is required for pro-apoptotic JNK activation (PubMed:22128169).Facilitates TNF-alpha-mediated recruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A and regulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation (PubMed:24130170).Inhibits PPP1CA phosphatase a
Has E3 ubiquitin-protein ligase activity (PubMed:24130170).Acts as an anti-apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a scaffold protein that is required for pro-apoptotic JNK activation (PubMed:22128169).Facilitates TNF-alpha-mediated recruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A and regulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation (PubMed:24130170).Inhibits PPP1CA phosphatase activity (PubMed:19945436, PubMed:19389623).
- Size: 100.0ul
- Molecular Weight: 20/24/79kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze/thaw cycles.
- Application: WB
- Brand: Saint Michael
- Catalogue No.: K114467P-100.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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