Anti-TBC1D23 Polyclonal Antibody, 50.0ul

Putative Rab GTPase-activating protein which plays a role in vesicular trafficking.Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles.Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1.Plays a role in brain development, including in cortical neuron positioning (By similarity).May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity).May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge (By similarity).

• Size: 50.0ul
• Molecular Weight: 77/78kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Application: WB
• Brand: Saint Michael
• Catalogue No.: K112323P-50.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.