Anti-TGFB3 Polyclonal Antibody, 100.0ul

£529.66
Delivery: 2 weeks
SKU
K005854P-100.0ul
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a late

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1.

  • Size: 100.0ul
  • Molecular Weight: 47kDa
  • Physical State: Liquid
  • Storage: Store at -20℃. Avoid freeze/thaw cycles.
  • Application: WB;IHC
  • Brand: Saint Michael
  • Catalogue No.: K005854P-100.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.

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