Anti-TMEM30A Polyclonal Antibody, 50.0ul

Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids.The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth,and, reconstituted to liposomes, predomiminantly transports phosphatidylserine and to a lesser extent phosphatidylethanolamine. The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine at the plasma membrane. Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes.

• Size: 50.0ul
• Molecular Weight: 28/37/41kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze/thaw cycles.
• Application: WB;IHC;ELISA
• Brand: Saint Michael
• Catalogue No.: K109691P-50.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.