Anti-TOR3A Polyclonal Antibody, 100.0ul

Torsin3A is a 397 amino acid member of the clpA/clpB family of proteins. Localized to the cytoplasm and the endoplasmic reticulum, Torsin3A is most highly expressed in stomach, lymph nodes and salivary glands. Torsin3A contains a hydrophobic N-terminal sequence, an ATP binding domain and 8 putative phosphorylation sites. Highly homologous with TorsinA and TorsinB, Torsin3A is thought to be related to the AAA chaperone-like family of ATPases. Members of this family play a role in the assembly, disassembly and operation of a variety of protein complexes, confer increased tolerance to high temperature and promote specific proteolysis. Torsin3A is also referred to as an interferon responsive gene, as interaction with type 1 interferons (IFN-alpha and IFN-beta) cause a 5 to 40 fold increase in Torsin3A mRNA levels. Three isoforms of Torsin3A exist as a result of alternative splicing events, and isoform 2 is expressed exclusively in the placenta

• Size: 100.0ul
• Molecular Weight: 21/39/46kDa
• Physical State: Liquid
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Application: IHC
• Brand: Saint Michael
• Catalogue No.: K115196P-100.0ul

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.