Anti-ZAP-70(PE) Monoclonal Antibody, 25.0T

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

• Size: 25.0T
• Physical State: Liquid
• Storage: Store at 4℃ in dark.Do not freeze.
• Application: FCM
• Brand: Saint Michael
• Catalogue No.: K011185M-25.0T

For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.