Anti-ZNF598 Polyclonal Antibody, 50.0ul
£145.11
Delivery: 2 weeks
SKU
K109259P-50.0ul
E3 ubiquitin-protein ligase that plays a key role in the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation. Required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40S ribosomal protein RPS10/eS10, RPS20/uS10 and RPS3/uS3. Stalling precludes synthesis of a long poly-lysine tail and initiates the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide. Also
E3 ubiquitin-protein ligase that plays a key role in the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation. Required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40S ribosomal protein RPS10/eS10, RPS20/uS10 and RPS3/uS3. Stalling precludes synthesis of a long poly-lysine tail and initiates the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide. Also acts as a component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation.
- Size: 50.0ul
- Molecular Weight: 34/98kDa
- Physical State: Liquid
- Storage: Store at -20℃. Avoid freeze/thaw cycles.
- Application: IHC
- Brand: Saint Michael
- Catalogue No.: K109259P-50.0ul
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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