It is a small molecule in vivo autophagy activator that covalently targets cysteine 277 in the ATP6V1A subunit of lysosomal V-ATPase. En6-mediated ATP6V1A modification uncoupled V-ATPase from Rag, resulting in inhibition of mTORC1 signaling, increased lysosomal acidification, and activation of autophagy.
- Size: 1mg
- Purity: ≥98%
- Molecular Formula: C 1 9 H 1 4 F 2 N 4 O 2
- Molecular Weight: 368.34
- Physical State: White to off-white Solid
- Storage: Powder:2-8℃, 2 years;Insolvent(Mother Liquid):-20℃, 6 months;-80℃, 1 year
- Brand: Saint Michael
- Catalogue No.: IE1900-1mg
For laboratory research use only. Not for human or animal consumption, diagnostic or therapeutic use.
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